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Glycoursodeoxycholic acid

CAS No. 64480-66-6

Glycoursodeoxycholic acid ( Ursodeoxycholylglycine | GUDCA )

产品货号. M19973 CAS No. 64480-66-6

甘糖去氧胆酸是一种酰基甘氨酸和胆汁酸-甘氨酸缀合物。它是通过结肠环境微生物菌群中存在的酶的作用产生的次级胆汁酸。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥441 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Glycoursodeoxycholic acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    甘糖去氧胆酸是一种酰基甘氨酸和胆汁酸-甘氨酸缀合物。它是通过结肠环境微生物菌群中存在的酶的作用产生的次级胆汁酸。
  • 产品描述
    Glycoursodeoxycholic acid is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment. In hepatocytes both primary and secondary bile acids undergo amino acid conjugation at the C-24 carboxylic acid on the side chain and almost all bile acids in the bile duct therefore exist in a glycine conjugated form. Bile acids are steroid acids found predominantly in bile of mammals.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    Ursodeoxycholylglycine | GUDCA
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    64480-66-6
  • 分子量
    449.62
  • 分子式
    C26H43NO5
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 10 mg/mL;Ethanol: 2 mg/mL
  • SMILES
    C[C@H](CCC(=O)NCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Goto T et al. LC/ESI-tandem mass spectrometric determination of bile acid 3-sulfates in human urine 3beta-Sulfooxy-12alpha-hydroxy-5beta-cholanoic acid is an abundant nonamidated sulfate. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Feb 1;846(1-2):69-77.
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